
王丽娜,教授,博士生导师。博士毕业于中国科学院大连化学物理研究所。主要研究方向为代谢和肿瘤免疫。以第一通讯作者在Immunity (Featured Article), Nature Chemical Biology, Nature Communications, Advanced Science, Molecular Therapy等学术期刊上发表10余篇SCI论文。获批国家发明专利1项。获批辽宁省“兴辽英才计划”青年拔尖人才、辽宁省“百千万人才工程”、辽宁省教育厅科技创新团队负责人,入选大连市青年科技之星,获评大连医科大学优秀教师。主持国家自然科学基金面上项目(2项)和青年项目、中国博士后科学基金特别资助项目和面上项目、辽宁省自然科学基金面上项目等。
代表性论著:
1.Lina Wang; Siru Li; Kai Wang; Na Wang; Qiaoling Liu; Zhen Sun; Li Wang; Lulu Wang; Quentin Liu; Chengli Song; Qingkai Yang. Spermine enhances antiviral and anticancer responses by stabilizing DNA binding with the DNA sensor cGAS,Immunity (Featured Article),2023, 56(2): 272-288.
2.Lina Wang; Qiaoling Liu; Na Wang; Siru Li; Wei Bian; Zhen Sun; Lulu Wang; Li Wang; Caigang Liu; Chengli Song; Quentin Liu; Qingkai Yang. Oleic acid dissolves cGAS–DNA phase separation to inhibit immune surveillance,Advanced Science, 2023, 10(14): e2206820.
3.Lina Wang; Siru Li; Kai Wang; Na Wang; Qiaoling Liu; Zhen Sun; Li Wang; Lulu Wang; Quentin Liu; Chengli Song; Caigang Liu; Qingkai Yang. DNA mechanical flexibility controls DNA potential to activate cGAS-mediated immune surveillance,Nature Communications,2022, 13(1): 7107.
4. Na Wang; Qiaoling Liu; Bo Wang; Zhuo Yang; Siru Li; Ran Li; Xinyuan Liang; Jiayu Fan; Hui Wang; Zhen Sun; Ling Dong; Yueru Hou; Shengnan Wang; Chengli Song; Yang Wang; Chunshan Quan; Qingkai Yang;Lina Wang. Host RNA N6-methyladenosine and incoming DNA N6-methyldeoxyadenosine modifications cooperatively elevate the condensation potential of DNA to activate immune surveillance,Molecular Therapy. 2024, 32(12): 4418-4434.
5.Chengli Song;Lina Wang; Xiaoyan Wu; Kai Wang; Dan Xie; Qi Xiao; Songyu Li; Kui Jiang; Lujian Liao; John R. Yates III; Jiing-Dwan Lee; Qingkai Yang. PML recruits TET2 to regulate DNA modification and cell proliferation in response to chemotherapeutic agent,Cancer Research, 2018, 78(10): 2475-2489.
招生专业:生物化学与分子生物学
电子邮箱:li-nawang@dmu.edu.cn