王翔，医学博士，副教授，硕士生导师。

2013年博士毕业于中南大学湘雅医学院病理学系，同年入职大连医科大学肿瘤干细胞研究院。目前，主要利用高通量测序和生物信息学等方法开展肿瘤多组学的研究，主持国家自然科学基金项目2项，以通讯或第一作者在Leukemia、Cell Death & Differentiation等期刊发表学术论文多篇，担任Nature Communications审稿专家。

研究方向

运用高通量测序（二代、三代测序）技术和生物信息学手段，开展肿瘤基因组学、转录组学和表观组学研究；开发新的高通量测序分析工具；基于人工智能算法开发生物制造技术以及病理图像识别工具。

代表性论文(*为通讯作者; #为共同第一作者)

1. Yingxue Mei, Xiang Wang*. RNA modification in mRNA cancer vaccines. Clinical and Experimental Medicine. 2023, 1-15.

2. Dong Li, Ying Ge, Ze Zhao, Rui Zhu, Xiang Wang*, Xiaolin Bi*. Distinct and Coordinated regulation of small non-coding RNAs by E2f1 and p53 during Drosophila development and in response to DNA damage. Frontiers in Cell and Developmental Biology. 2021, 9: 695311.

3. Lipin Ren, Yanjie Shang, Li Yang, Shiwen Wang, Xiang Wang, Shan Chen, Zhigui Bao, Dong An, Fanming Meng, Jifeng Cai, Yadong Guo*. Chromosome-level de novo genome assembly of Sarcophaga peregrina provides insights into the evolutionary adaptation of flesh flies. Molecular ecology resources. 2021, 21(1): 251-262.

4. Xingyun Wang#, Shilin Xia#, Hongchang Li#, Xiang Wang#, Chaonan Li, Yulin Chao, Lingqiang Zhang*, Chuanchun Han*. The deubiquitinase USP10 regulates KLF4 stability and suppresses lung tumorigenesis. Cell Death & Differentiation. 2020, 27(6): 1747-1764.

5. Yizhu Lyu, Jiacheng Lou, Yan Yang, Jiuxing Feng, Yuchao Hao, Shuyu Huang, Linlin Yin, Jiangbing Xu, Dan Huang, Binbin Ma, Deyu Zou, Yue Wang, Yue Zhang, Bo Zhang, Puxiang Chen, Kanglun Yu, Eric W.-F. Lam, Xiang Wang*, Quentin Liu*, Jinsong Yan*, Bilian Jin*. Dysfunction of the WT1-MEG3 signaling promotes AML leukemogenesis via p53-dependent and -independent pathways. Leukemia. 2017, 31(12): 2543-2551.

联系方式

电子邮箱：wangx6281@dmu.edu.cn